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Projects
Specialties
Strategic Theme of Health and Medical Technologies
Technology Applications
4 project(s) found
Dentistry
Induction of osteogenic differentiation in a rat calvarial bone defect model using an In situ forming graphene oxide incorporated glycol chitosan/oxidized hyaluronic acid injectable hydrogel
Injectable glycol chitosan/oxidized hyaluronic acid hydrogel encapsulating graphene oxide was prepared via self-crosslinking. Then, hydrogel's cellular activities and physico-chemical properties are investigated in vitro and in vivo. We believe that our system will be able to act as a facile delivery vehicle of cells, nano/microparticles, and growth factors for use in tissue engineering & regenerative medicine
Dentistry
A reduced metagenome technique (2bRAD-M) enables characterization of low-biomass microbiomes in clinical settings
The microbiome can present in ultralow biomass in various human clinical samples (i.e., blood, tumor tissues, etc.). It creates tremendous disease diagnosis or prediction opportunities, yet imposes notable technical challenges to conventional metagenomics methods for microbial taxonomic and functional profiling. 2bRAD-M has demonstrated its unique capability in detecting micro-organisms in ultralow biomass, mixed with abundant host cells, or with severe DNA degradation (PMID: 35078506).
Engineering
New-generation Intelligent Label-free Imaging Cytometry for Health and Disease
Develop new integrative live-cell image-based screening strategies to identify new cost-effective morphological biomarkers of diseases that are linked to the patients' molecular profiles, transforming our practice in precision medicine.